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Alterations in fecal short-chain fatty acids in patients with irritable bowel syndrome: A systematic review and meta-analysis

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Moreover, exposure to IGF binding protein 5 (IGFBP5), the transport protein of IGF-1, provoked cellular senescence in human umbilical vein endothelial cells (HUVEC) [148] although the signaling pathway remained unknown

Both approaches significantly lowered HbA1c levels (weighted mean difference [WMD] 0.75%, 95% CI 0.97 to 0.53) but increased hypoglycemic risk [risk ratio (RR) 7.59, 95% CI 3.3517.17] compared to the unchanged GLP-1RA